An Outbreak of Covid-19 on an Aircraft Carrier.
Identifieur interne : 000235 ( Main/Exploration ); précédent : 000234; suivant : 000236An Outbreak of Covid-19 on an Aircraft Carrier.
Auteurs : Matthew R. Kasper ; Jesse R. Geibe ; Christine L. Sears ; Asha J. Riegodedios ; Tina Luse ; Annette M. Von Thun ; Michael B. Mcginnis ; Niels Olson ; Daniel Houskamp ; Robert Fenequito ; Timothy H. Burgess ; Adam W. Armstrong ; Gerald Delong ; Robert J. Hawkins ; Bruce L. GillinghamSource :
- The New England journal of medicine [ 1533-4406 ] ; 2020.
Abstract
BACKGROUND
An outbreak of coronavirus disease 2019 (Covid-19) occurred on the U.S.S.
METHODS
We obtained clinical and demographic data for all crew members, including results of testing by real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). All crew members were followed up for a minimum of 10 weeks, regardless of test results or the absence of symptoms.
RESULTS
The crew was predominantly young (mean age, 27 years) and was in general good health, meeting U.S. Navy standards for sea duty. Over the course of the outbreak, 1271 crew members (26.6% of the crew) tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by rRT-PCR testing, and more than 1000 infections were identified within 5 weeks after the first laboratory-confirmed infection. An additional 60 crew members had suspected Covid-19 (i.e., illness that met Council of State and Territorial Epidemiologists clinical criteria for Covid-19 without a positive test result). Among the crew members with laboratory-confirmed infection, 76.9% (978 of 1271) had no symptoms at the time that they tested positive and 55.0% had symptoms develop at any time during the clinical course. Among the 1331 crew members with suspected or confirmed Covid-19, 23 (1.7%) were hospitalized, 4 (0.3%) received intensive care, and 1 died. Crew members who worked in confined spaces appeared more likely to become infected.
CONCLUSIONS
SARS-CoV-2 spread quickly among the crew of the U.S.S.
DOI: 10.1056/NEJMoa2019375
PubMed: 33176077
PubMed Central: PMC7675688
Affiliations:
Links toward previous steps (curation, corpus...)
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">An Outbreak of Covid-19 on an Aircraft Carrier.</title><author><name sortKey="Kasper, Matthew R" sort="Kasper, Matthew R" uniqKey="Kasper M" first="Matthew R" last="Kasper">Matthew R. Kasper</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Geibe, Jesse R" sort="Geibe, Jesse R" uniqKey="Geibe J" first="Jesse R" last="Geibe">Jesse R. Geibe</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Sears, Christine L" sort="Sears, Christine L" uniqKey="Sears C" first="Christine L" last="Sears">Christine L. Sears</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Riegodedios, Asha J" sort="Riegodedios, Asha J" uniqKey="Riegodedios A" first="Asha J" last="Riegodedios">Asha J. Riegodedios</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Luse, Tina" sort="Luse, Tina" uniqKey="Luse T" first="Tina" last="Luse">Tina Luse</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Von Thun, Annette M" sort="Von Thun, Annette M" uniqKey="Von Thun A" first="Annette M" last="Von Thun">Annette M. Von Thun</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Mcginnis, Michael B" sort="Mcginnis, Michael B" uniqKey="Mcginnis M" first="Michael B" last="Mcginnis">Michael B. Mcginnis</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Olson, Niels" sort="Olson, Niels" uniqKey="Olson N" first="Niels" last="Olson">Niels Olson</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Houskamp, Daniel" sort="Houskamp, Daniel" uniqKey="Houskamp D" first="Daniel" last="Houskamp">Daniel Houskamp</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Fenequito, Robert" sort="Fenequito, Robert" uniqKey="Fenequito R" first="Robert" last="Fenequito">Robert Fenequito</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Burgess, Timothy H" sort="Burgess, Timothy H" uniqKey="Burgess T" first="Timothy H" last="Burgess">Timothy H. Burgess</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Armstrong, Adam W" sort="Armstrong, Adam W" uniqKey="Armstrong A" first="Adam W" last="Armstrong">Adam W. Armstrong</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Delong, Gerald" sort="Delong, Gerald" uniqKey="Delong G" first="Gerald" last="Delong">Gerald Delong</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Hawkins, Robert J" sort="Hawkins, Robert J" uniqKey="Hawkins R" first="Robert J" last="Hawkins">Robert J. Hawkins</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Gillingham, Bruce L" sort="Gillingham, Bruce L" uniqKey="Gillingham B" first="Bruce L" last="Gillingham">Bruce L. Gillingham</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:33176077</idno><idno type="pmid">33176077</idno><idno type="doi">10.1056/NEJMoa2019375</idno><idno type="pmc">PMC7675688</idno><idno type="wicri:Area/Main/Corpus">000043</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000043</idno><idno type="wicri:Area/Main/Curation">000043</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000043</idno><idno type="wicri:Area/Main/Exploration">000043</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">An Outbreak of Covid-19 on an Aircraft Carrier.</title><author><name sortKey="Kasper, Matthew R" sort="Kasper, Matthew R" uniqKey="Kasper M" first="Matthew R" last="Kasper">Matthew R. Kasper</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Geibe, Jesse R" sort="Geibe, Jesse R" uniqKey="Geibe J" first="Jesse R" last="Geibe">Jesse R. Geibe</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Sears, Christine L" sort="Sears, Christine L" uniqKey="Sears C" first="Christine L" last="Sears">Christine L. Sears</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Riegodedios, Asha J" sort="Riegodedios, Asha J" uniqKey="Riegodedios A" first="Asha J" last="Riegodedios">Asha J. Riegodedios</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Luse, Tina" sort="Luse, Tina" uniqKey="Luse T" first="Tina" last="Luse">Tina Luse</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Von Thun, Annette M" sort="Von Thun, Annette M" uniqKey="Von Thun A" first="Annette M" last="Von Thun">Annette M. Von Thun</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Mcginnis, Michael B" sort="Mcginnis, Michael B" uniqKey="Mcginnis M" first="Michael B" last="Mcginnis">Michael B. Mcginnis</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Olson, Niels" sort="Olson, Niels" uniqKey="Olson N" first="Niels" last="Olson">Niels Olson</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Houskamp, Daniel" sort="Houskamp, Daniel" uniqKey="Houskamp D" first="Daniel" last="Houskamp">Daniel Houskamp</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Fenequito, Robert" sort="Fenequito, Robert" uniqKey="Fenequito R" first="Robert" last="Fenequito">Robert Fenequito</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Burgess, Timothy H" sort="Burgess, Timothy H" uniqKey="Burgess T" first="Timothy H" last="Burgess">Timothy H. Burgess</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Armstrong, Adam W" sort="Armstrong, Adam W" uniqKey="Armstrong A" first="Adam W" last="Armstrong">Adam W. Armstrong</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Delong, Gerald" sort="Delong, Gerald" uniqKey="Delong G" first="Gerald" last="Delong">Gerald Delong</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Hawkins, Robert J" sort="Hawkins, Robert J" uniqKey="Hawkins R" first="Robert J" last="Hawkins">Robert J. Hawkins</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author><author><name sortKey="Gillingham, Bruce L" sort="Gillingham, Bruce L" uniqKey="Gillingham B" first="Bruce L" last="Gillingham">Bruce L. Gillingham</name><affiliation><nlm:affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</nlm:affiliation><wicri:noCountry code="subField">Silver Spring (A.W.A.)</wicri:noCountry></affiliation></author></analytic><series><title level="j">The New England journal of medicine</title><idno type="eISSN">1533-4406</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>An outbreak of coronavirus disease 2019 (Covid-19) occurred on the U.S.S. </p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>We obtained clinical and demographic data for all crew members, including results of testing by real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). All crew members were followed up for a minimum of 10 weeks, regardless of test results or the absence of symptoms.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>The crew was predominantly young (mean age, 27 years) and was in general good health, meeting U.S. Navy standards for sea duty. Over the course of the outbreak, 1271 crew members (26.6% of the crew) tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by rRT-PCR testing, and more than 1000 infections were identified within 5 weeks after the first laboratory-confirmed infection. An additional 60 crew members had suspected Covid-19 (i.e., illness that met Council of State and Territorial Epidemiologists clinical criteria for Covid-19 without a positive test result). Among the crew members with laboratory-confirmed infection, 76.9% (978 of 1271) had no symptoms at the time that they tested positive and 55.0% had symptoms develop at any time during the clinical course. Among the 1331 crew members with suspected or confirmed Covid-19, 23 (1.7%) were hospitalized, 4 (0.3%) received intensive care, and 1 died. Crew members who worked in confined spaces appeared more likely to become infected.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>SARS-CoV-2 spread quickly among the crew of the U.S.S. </p></div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">33176077</PMID><DateRevised><Year>2020</Year><Month>12</Month><Day>01</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1533-4406</ISSN><JournalIssue CitedMedium="Internet"><PubDate><Year>2020</Year><Month>Nov</Month><Day>11</Day></PubDate></JournalIssue><Title>The New England journal of medicine</Title><ISOAbbreviation>N Engl J Med</ISOAbbreviation></Journal><ArticleTitle>An Outbreak of Covid-19 on an Aircraft Carrier.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1056/NEJMoa2019375</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">An outbreak of coronavirus disease 2019 (Covid-19) occurred on the U.S.S. <i>Theodore Roosevelt</i>, a nuclear-powered aircraft carrier with a crew of 4779 personnel.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We obtained clinical and demographic data for all crew members, including results of testing by real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). All crew members were followed up for a minimum of 10 weeks, regardless of test results or the absence of symptoms.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The crew was predominantly young (mean age, 27 years) and was in general good health, meeting U.S. Navy standards for sea duty. Over the course of the outbreak, 1271 crew members (26.6% of the crew) tested positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by rRT-PCR testing, and more than 1000 infections were identified within 5 weeks after the first laboratory-confirmed infection. An additional 60 crew members had suspected Covid-19 (i.e., illness that met Council of State and Territorial Epidemiologists clinical criteria for Covid-19 without a positive test result). Among the crew members with laboratory-confirmed infection, 76.9% (978 of 1271) had no symptoms at the time that they tested positive and 55.0% had symptoms develop at any time during the clinical course. Among the 1331 crew members with suspected or confirmed Covid-19, 23 (1.7%) were hospitalized, 4 (0.3%) received intensive care, and 1 died. Crew members who worked in confined spaces appeared more likely to become infected.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">SARS-CoV-2 spread quickly among the crew of the U.S.S. <i>Theodore Roosevelt</i>. Transmission was facilitated by close-quarters conditions and by asymptomatic and presymptomatic infected crew members. Nearly half of those who tested positive for the virus never had symptoms.</AbstractText><CopyrightInformation>Copyright © 2020 Massachusetts Medical Society.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kasper</LastName><ForeName>Matthew R</ForeName><Initials>MR</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Geibe</LastName><ForeName>Jesse R</ForeName><Initials>JR</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sears</LastName><ForeName>Christine L</ForeName><Initials>CL</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Riegodedios</LastName><ForeName>Asha J</ForeName><Initials>AJ</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Luse</LastName><ForeName>Tina</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Von Thun</LastName><ForeName>Annette M</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McGinnis</LastName><ForeName>Michael B</ForeName><Initials>MB</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Olson</LastName><ForeName>Niels</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Houskamp</LastName><ForeName>Daniel</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fenequito</LastName><ForeName>Robert</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Burgess</LastName><ForeName>Timothy H</ForeName><Initials>TH</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Armstrong</LastName><ForeName>Adam W</ForeName><Initials>AW</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>DeLong</LastName><ForeName>Gerald</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hawkins</LastName><ForeName>Robert J</ForeName><Initials>RJ</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gillingham</LastName><ForeName>Bruce L</ForeName><Initials>BL</Initials><AffiliationInfo><Affiliation>From the U.S. Navy Bureau of Medicine and Surgery, Falls Church (M.R.K., B.L.G.), and the Navy and Marine Corps Public Health Center, Portsmouth (J.R.G., A.J.R., T.L., A.M.V.T., G.D., R.J.H.) - both in Virginia; U.S. Navy Seventh Fleet, Yokosuka, Japan (C.L.S.); U.S. Pacific Fleet, Pearl Harbor, Hawaii (M.B.M.); the U.S. Naval Hospital Guam, Apra Harbor (N.O., D.H., R.F.); and the Uniformed Services University of the Health Sciences, Bethesda (T.H.B.), and the Naval Medical Research Center, Silver Spring (A.W.A.) - both in Maryland.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>11</Month><Day>11</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>N Engl J Med</MedlineTA><NlmUniqueID>0255562</NlmUniqueID><ISSNLinking>0028-4793</ISSNLinking></MedlineJournalInfo><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>11</Month><Day>11</Day><Hour>17</Hour><Minute>16</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>11</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>11</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33176077</ArticleId><ArticleId IdType="doi">10.1056/NEJMoa2019375</ArticleId><ArticleId IdType="pmc">PMC7675688</ArticleId></ArticleIdList><ReferenceList><Reference><Citation>Int J Infect Dis. 2020 Apr;93:201-204</Citation><ArticleIdList><ArticleId IdType="pubmed">32097725</ArticleId></ArticleIdList></Reference><Reference><Citation>Emerg Infect Dis. 2001 May-Jun;7(3):463-5</Citation><ArticleIdList><ArticleId IdType="pubmed">11384530</ArticleId></ArticleIdList></Reference><Reference><Citation>MMWR Morb Mortal Wkly Rep. 2020 Apr 10;69(14):422-426</Citation><ArticleIdList><ArticleId IdType="pubmed">32271728</ArticleId></ArticleIdList></Reference><Reference><Citation>PLoS One. 2011;6(6):e20822</Citation><ArticleIdList><ArticleId IdType="pubmed">21713034</ArticleId></ArticleIdList></Reference><Reference><Citation>N Engl J Med. 2020 Jun 11;382(24):2372-2374</Citation><ArticleIdList><ArticleId IdType="pubmed">32302078</ArticleId></ArticleIdList></Reference><Reference><Citation>MMWR Morb Mortal Wkly Rep. 2020 Apr 03;69(13):382-386</Citation><ArticleIdList><ArticleId IdType="pubmed">32240123</ArticleId></ArticleIdList></Reference><Reference><Citation>J Clin Med. 2020 Jun 05;9(6):</Citation><ArticleIdList><ArticleId IdType="pubmed">32516940</ArticleId></ArticleIdList></Reference><Reference><Citation>JAMA. 2020 Apr 21;323(15):1488-1494</Citation><ArticleIdList><ArticleId IdType="pubmed">32125362</ArticleId></ArticleIdList></Reference><Reference><Citation>Nat Med. 2020 May;26(5):672-675</Citation><ArticleIdList><ArticleId IdType="pubmed">32296168</ArticleId></ArticleIdList></Reference><Reference><Citation>MMWR Morb Mortal Wkly Rep. 2020 Mar 27;69(12):343-346</Citation><ArticleIdList><ArticleId IdType="pubmed">32214079</ArticleId></ArticleIdList></Reference><Reference><Citation>MMWR Morb Mortal Wkly Rep. 2020 Jun 12;69(23):714-721</Citation><ArticleIdList><ArticleId IdType="pubmed">32525850</ArticleId></ArticleIdList></Reference><Reference><Citation>MMWR Morb Mortal Wkly Rep. 2020 Mar 20;69(11):312-313</Citation><ArticleIdList><ArticleId IdType="pubmed">32191689</ArticleId></ArticleIdList></Reference><Reference><Citation>MMWR Morb Mortal Wkly Rep. 2020 Apr 17;69(15):458-464</Citation><ArticleIdList><ArticleId IdType="pubmed">32298251</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Armstrong, Adam W" sort="Armstrong, Adam W" uniqKey="Armstrong A" first="Adam W" last="Armstrong">Adam W. Armstrong</name><name sortKey="Burgess, Timothy H" sort="Burgess, Timothy H" uniqKey="Burgess T" first="Timothy H" last="Burgess">Timothy H. Burgess</name><name sortKey="Delong, Gerald" sort="Delong, Gerald" uniqKey="Delong G" first="Gerald" last="Delong">Gerald Delong</name><name sortKey="Fenequito, Robert" sort="Fenequito, Robert" uniqKey="Fenequito R" first="Robert" last="Fenequito">Robert Fenequito</name><name sortKey="Geibe, Jesse R" sort="Geibe, Jesse R" uniqKey="Geibe J" first="Jesse R" last="Geibe">Jesse R. Geibe</name><name sortKey="Gillingham, Bruce L" sort="Gillingham, Bruce L" uniqKey="Gillingham B" first="Bruce L" last="Gillingham">Bruce L. Gillingham</name><name sortKey="Hawkins, Robert J" sort="Hawkins, Robert J" uniqKey="Hawkins R" first="Robert J" last="Hawkins">Robert J. Hawkins</name><name sortKey="Houskamp, Daniel" sort="Houskamp, Daniel" uniqKey="Houskamp D" first="Daniel" last="Houskamp">Daniel Houskamp</name><name sortKey="Kasper, Matthew R" sort="Kasper, Matthew R" uniqKey="Kasper M" first="Matthew R" last="Kasper">Matthew R. Kasper</name><name sortKey="Luse, Tina" sort="Luse, Tina" uniqKey="Luse T" first="Tina" last="Luse">Tina Luse</name><name sortKey="Mcginnis, Michael B" sort="Mcginnis, Michael B" uniqKey="Mcginnis M" first="Michael B" last="Mcginnis">Michael B. Mcginnis</name><name sortKey="Olson, Niels" sort="Olson, Niels" uniqKey="Olson N" first="Niels" last="Olson">Niels Olson</name><name sortKey="Riegodedios, Asha J" sort="Riegodedios, Asha J" uniqKey="Riegodedios A" first="Asha J" last="Riegodedios">Asha J. Riegodedios</name><name sortKey="Sears, Christine L" sort="Sears, Christine L" uniqKey="Sears C" first="Christine L" last="Sears">Christine L. Sears</name><name sortKey="Von Thun, Annette M" sort="Von Thun, Annette M" uniqKey="Von Thun A" first="Annette M" last="Von Thun">Annette M. Von Thun</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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